- Analyze samples of biological material for chemical content or reaction.
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- Count numbers of chromosomes and identify the structural abnormalities by viewing culture slides through microscopes, light microscopes, or photomicroscopes.
- Examine chromosomes found in biological specimens to detect abnormalities.
- Analyze chromosomes found in biological specimens to aid diagnoses and treatments for genetic diseases such as congenital birth defects, fertility problems, and hematological disorders.
- Recognize and report abnormalities in the color, size, shape, composition, or pattern of cells.
- Arrange and attach chromosomes in numbered pairs on karyotype charts, using standard genetics laboratory practices and nomenclature, to identify normal or abnormal chromosomes.
- Apply prepared specimen and control to appropriate grid, run instrumentation, and produce analyzable results.
- Select appropriate culturing system or procedure based on specimen type and reason for referral.
- Harvest cell cultures using substances such as mitotic arrestants, cell releasing agents, and cell fixatives.
- Summarize test results and report to appropriate authorities.
- Prepare biological specimens such as amniotic fluids, bone marrow, tumors, chorionic villi, and blood, for chromosome examinations.
- Select or prepare specimens and media for cell cultures using aseptic techniques, knowledge of medium components, or cell nutritional requirements.
- Input details of specimen processing, analysis, and technical issues into logs or laboratory information systems (LIS).
- Prepare slides of cell cultures following standard procedures.
- Input details of specimens into logs or computer systems.
- Select appropriate methods of preparation and storage of media to maintain potential of hydrogen (pH), sterility, or ability to support growth.
- Develop, implement, and monitor quality control and quality assurance programs to ensure accurate and precise test performance and reports.
- Stain slides to make chromosomes visible for microscopy.
- Describe chromosome, FISH and aCGH analysis results in International System of Cytogenetic Nomenclature (ISCN) language.
- Evaluate appropriateness of received specimens for requested tests.
- Create chromosome images using computer imaging systems.
- Determine optimal time sequences and methods for manual or robotic cell harvests.
- Communicate to responsible parties unacceptable specimens and suggest remediation for future submissions.
- Select banding methods to permit identification of chromosome pairs.
- Maintain laboratory equipment such as photomicroscopes, inverted microscopes, and standard darkroom equipment.
- Identify appropriate methods of specimen collection, preservation, or transport.
- Archive case documentation and study materials as required by regulations and laws.
- Supervise subordinate laboratory staff.
- Develop and implement training programs for trainees, medical students, resident physicians or post-doctoral fellows.
- Communicate test results or technical information to patients, physicians, family members, or researchers.
- Extract, measure, dilute as appropriate, label, and prepare DNA for array analysis.
- Count numbers of chromosomes and identify the structural abnormalities by viewing culture slides through microscopes, light microscopes, or photomicroscopes.
- Examine chromosomes found in biological specimens to detect abnormalities.
- Analyze chromosomes found in biological specimens to aid diagnoses and treatments for genetic diseases such as congenital birth defects, fertility problems, and hematological disorders.
- Recognize and report abnormalities in the color, size, shape, composition, or pattern of cells.
- Examine cell samples to detect abnormalities in the color, shape, or size of cellular components and patterns.
- Prepare and analyze samples, such as Papanicolaou (PAP) smear body fluids and fine needle aspirations (FNAs), to detect abnormal conditions.
- Examine specimens to detect abnormal hormone conditions.
- Document specimens by verifying patients' and specimens' information.
- Submit slides with abnormal cell structures to pathologists for further examination.
- Examine specimens, using microscopes, to evaluate specimen quality.
- Maintain effective laboratory operations by adhering to standards of specimen collection, preparation, or laboratory safety.
- Provide patient clinical data or microscopic findings to assist pathologists in the preparation of pathology reports.
- Assist pathologists or other physicians to collect cell samples by fine needle aspiration (FNA) biopsy or other method.
- Prepare cell samples by applying special staining techniques, such as chromosomal staining, to differentiate cells or cell components.
- Adjust, maintain, or repair laboratory equipment, such as microscopes.
- Assign tasks or coordinate task assignments to ensure adequate performance of laboratory activities.
- Attend continuing education programs that address laboratory issues.
- Examine cell samples to detect abnormalities in the color, shape, or size of cellular components and patterns.
- Prepare and analyze samples, such as Papanicolaou (PAP) smear body fluids and fine needle aspirations (FNAs), to detect abnormal conditions.
- Examine specimens to detect abnormal hormone conditions.
- Conduct chemical analyses of body fluids, such as blood or urine, using microscope or automatic analyzer to detect abnormalities or diseases and enter findings into computer.
- Examine cells stained with dye to locate abnormalities.
- Analyze the results of tests or experiments to ensure conformity to specifications, using special mechanical or electrical devices.
- Set up, maintain, calibrate, clean, and test sterility of medical laboratory equipment.
- Prepare standard volumetric solutions or reagents to be combined with samples, following standardized formulas or experimental procedures.
- Collect blood or tissue samples from patients, observing principles of asepsis to obtain blood sample.
- Supervise or instruct other technicians or laboratory assistants.
- Conduct blood tests for transfusion purposes and perform blood counts.
- Inoculate fertilized eggs, broths, or other bacteriological media with organisms.
- Obtain specimens, cultivating, isolating, and identifying microorganisms for analysis.
- Consult with a pathologist to determine a final diagnosis when abnormal cells are found.
- Cut, stain, and mount tissue samples for examination by pathologists.
- Perform medical research to further control or cure disease.
- Analyze and record test data to issue reports that use charts, graphs, or narratives.
- Test raw materials, processes, or finished products to determine quality or quantity of materials or characteristics of a substance.
- Conduct chemical analyses of body fluids, such as blood or urine, using microscope or automatic analyzer to detect abnormalities or diseases and enter findings into computer.
- Examine cells stained with dye to locate abnormalities.
- Analyze the results of tests or experiments to ensure conformity to specifications, using special mechanical or electrical devices.
- Examine microscopic samples to identify diseases or other abnormalities.
- Conduct genetic analyses of deoxyribonucleic acid (DNA) or chromosomes to diagnose small biopsies and cell samples.
- Diagnose diseases or study medical conditions, using techniques such as gross pathology, histology, cytology, cytopathology, clinical chemistry, immunology, flow cytometry, or molecular biology.
- Write pathology reports summarizing analyses, results, and conclusions.
- Communicate pathologic findings to surgeons or other physicians.
- Identify the etiology, pathogenesis, morphological change, and clinical significance of diseases.
- Read current literature, talk with colleagues, or participate in professional organizations or conferences to keep abreast of developments in pathology.
- Consult with physicians about ordering and interpreting tests or providing treatments.
- Analyze and interpret results from tests, such as microbial or parasite tests, urine analyses, hormonal assays, fine needle aspirations (FNAs), and polymerase chain reactions (PCRs).
- Review cases by analyzing autopsies, laboratory findings, or case investigation reports.
- Manage medical laboratories.
- Develop or adopt new tests or instruments to improve diagnosis of diseases.
- Educate physicians, students, and other personnel in medical laboratory professions, such as medical technology, cytotechnology, or histotechnology.
- Plan and supervise the work of the pathology staff, residents, or visiting pathologists.
- Perform autopsies to determine causes of deaths.
- Diagnose infections, such as Hepatitis B and Acquired Immune Deficiency Syndrome (AIDS), by conducting tests to detect the antibodies that patients' immune systems make to fight such infections.
- Obtain specimens by performing procedures, such as biopsies or fine needle aspirations (FNAs) of superficial nodules.
- Conduct research and present scientific findings.
- Testify in depositions or trials as an expert witness.
- Examine microscopic samples to identify diseases or other abnormalities.
- Conduct genetic analyses of deoxyribonucleic acid (DNA) or chromosomes to diagnose small biopsies and cell samples.
- Identify tissue structures or cell components to be used in the diagnosis, prevention, or treatment of diseases.
- Examine slides under microscopes to ensure tissue preparation meets laboratory requirements.
- Compile and maintain records of preventive maintenance and instrument performance checks according to schedule and regulations.
- Compile materials for distribution to pathologists, such as surgical working drafts, requisitions, and slides.
- Cut sections of body tissues for microscopic examination, using microtomes.
- Embed tissue specimens into paraffin wax blocks, or infiltrate tissue specimens with wax.
- Operate computerized laboratory equipment to dehydrate, decalcify, or microincinerate tissue samples.
- Perform electron microscopy or mass spectrometry to analyze specimens.
- Perform procedures associated with histochemistry to prepare specimens for immunofluorescence or microscopy.
- Perform tests by following physician instructions.
- Prepare or use prepared tissue specimens for teaching, research or diagnostic purposes.
- Prepare substances, such as reagents and dilution, and stains for histological specimens according to protocols.
- Resolve problems with laboratory equipment and instruments, such as microscopes, mass spectrometers, microtomes, immunostainers, tissue processors, embedding centers, and water baths.
- Stain tissue specimens with dyes or other chemicals to make cell details visible under microscopes.
- Supervise histology laboratory activities.
- Teach students or other staff.
- Identify tissue structures or cell components to be used in the diagnosis, prevention, or treatment of diseases.
- Examine slides under microscopes to ensure tissue preparation meets laboratory requirements.
- Perform laboratory analyses or physical inspections of samples to detect disease or to assess purity or cleanliness.
- Recommend measures to help protect workers from potentially hazardous work methods, processes, or materials.
- Inspect or evaluate workplace environments, equipment, or practices to ensure compliance with safety standards and government regulations.
- Collaborate with engineers or physicians to institute control or remedial measures for hazardous or potentially hazardous conditions or equipment.
- Develop or maintain hygiene programs, such as noise surveys, continuous atmosphere monitoring, ventilation surveys, or asbestos management plans.
- Coordinate "right-to-know" programs regarding hazardous chemicals or other substances.
- Conduct safety training or education programs and demonstrate the use of safety equipment.
- Investigate the adequacy of ventilation, exhaust equipment, lighting, or other conditions that could affect employee health, comfort, or performance.
- Analyze incident data to identify trends in injuries, illnesses, accidents, or other hazards.
- Investigate health-related complaints and inspect facilities to ensure that they comply with public health legislation and regulations.
- Collect samples of hazardous materials or arrange for sample collection.
- Maintain or update emergency response plans or procedures.
- Provide new-employee health and safety orientations and develop materials for these presentations.
- Inspect specified areas to ensure the presence of fire prevention equipment, safety equipment, or first-aid supplies.
- Maintain inventories of hazardous materials or hazardous wastes, using waste tracking systems to ensure that materials are handled properly.
- Develop or maintain medical monitoring programs for employees.
- Conduct audits at hazardous waste sites or industrial sites or participate in hazardous waste site investigations.
- Order suspension of activities that pose threats to workers' health or safety.
- Investigate accidents to identify causes or to determine how such accidents might be prevented in the future.
- Collect samples of dust, gases, vapors, or other potentially toxic materials for analysis.
- Prepare hazardous, radioactive, or mixed waste samples for transportation or storage by treating, compacting, packaging, and labeling them.
- Perform laboratory analyses or physical inspections of samples to detect disease or to assess purity or cleanliness.
