The Certified Pediatric Nurse Practitioner in acute care (CPNP-AC) provides family-centered and culturally respectful care for pediatric patients with acute, complex, critical, and chronic illness across a variety of care settings. The CPNP-AC works closely with an interprofessional team to provide the highest level of evidence-based care for infants, children, adolescents, and young adults with life-threatening illnesses and organ dysfunction or failure. Due to their unique health care needs, a patient outside the traditionally defined pediatric age parameters may be best served by the CPNP-AC. The practitioner in this role is responsible for independent and collaborative decision making with direct accountability for clinical judgment. The CPNP-AC monitors and ensures the quality of health care practice and assists the patient and family in negotiating health care delivery systems.